Breast Cancer Drug Pathway Analyzer 2013

NEW YORK, Oct.迷你倉 24, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:Breast Cancer Drug Pathway Analyzer 2013 .reportlinker.com/p01816738/Breast-Cancer-Drug-Pathway-Analyzer-2013.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_and_MedicationExtra value: One year of free online updates included with this productThere are today at least 504 targeted molecular therapies known to affect more than 252 specific intracellular signaling pathways for the treatment of breast cancer. The rational for this plethora of treatment strategies is based on our increasing understanding of the 270 drug targets that are included in this drug-pathway analyzing tool. No less than 266 of these have been recorded with mutations and 46 drug targets have mutations which have been causally implicated in cancer.Pathway Coverage- BioCarta# 250 Pathways- KEGG# 187 Pathways- NCI-Nature# 252 Pathways- NetPath# 32 PathwaysPipeline CoverageMarketed# 56Pre-registration# 2Phase III# 26Phase II# 177Phase I# 105Preclinical# 142No Data# 1Suspended# 8Ceased# 194The continuous identification of drug targets and pathways that are altered in cancer is not only crucial for our understanding of cancer biology, but also to search for new targets for early diagnosis and improved treatment designs. Consequently, it has never before been as important to rapidly translate systems biology of disease and therapeutics to actionable pipeline decisions to ensure that the optimal market conditions exist by the time a candidate drug is commercialized.For this reason BioSeeker, a leader in pipeline analytics, has constructed this high-level drug-pathway analyzer which lets you interact with the breast cancer pipeline in a whole different than way than you ever done before. Its capabilities moves you beyond powerful competitive intelligence to an opportunity seeking tool which lets you, by means of both present and emerging scientific knowledge, analyze the breast cancer pipeline for interesting compounds which affect and/or fit your purposes, may it be benchmarking, in/out-licensing, combination therapy options, drug repositioning, indication expansion etc.You Use this Analyzer Tool in breast cancer to:* Map the competition and find suitable benchmarking/licensing drugs based on specific pathways and drug properties* Uncover potential indication expansion areas for your drug portfolio* Reveal repositioning opportunities for your older, shelved drugs* Evaluate the progression and success of targeting certain pathways by different tumor types* Investigate drugs which affect crosstalk between key pathways* Investigate different combination therapy options available to you in various cancer types. Use this tool to look for the most-efficient ways to combine your drug with other targeted agents.* Find possible adjuvant therapy settings with other drugs.This is how you do it:In analyzing drug-pathway relationships this tool has three core modes:1. Select - You go right ahead and select any pathway for analysis2. Suggest - The tool can suggest pathways to you according to your pipeline specifications3. Compare - You can overlay any pathways with each other and do a comparative analysisYou can interactively analyze any breast cancer drug-pathway relationship by using up to four different pathway sources and further refine your analysis with up to 20 different pipeline parameters, including parameters such as presence of mutations, molecular function of targets, stage of development, sub-cellular localization and many more. Each parameter has multi-select options to them and can self storagee used as either an inclusion parameter or exclusion parameter.User Reports with GraphicsEach analysis report generated in the Drug Pathway Analyzer includes many different types of graphs and tables which can also be easily downloaded and dropped into applications such as PowerPoint for external presentations outside the tool.The Pathway Analyzer Comes Integrated with Pipeline InformationWith a simple click you can easily and quickly get relevant information about the drug being included in a specific pathway. A typical drug profile reports on, depending on stage of development and available information:Drug Name & SynonymsPresentation of drug name and synonymsPrincipal Company & PartnersPresentation of principal company and partners Target and Molecular Function of TargetDescribed target(s) is/are presented with:Official Gene Symbol - Chromosome Location - Gene & Protein Name - Molecular FunctionTarget LocalizationDescribed target(s) is/are presented with primary and alternate localizations.Target Expression ProfilesLinks to protein expression profile(s) of target(s) in various human tissues, cell lines and primary cells, including up to:48 different normal tissue types20 different types of cancer47 cell lines12 samples of primary blood cellsMutationAll targets are cross-referenced with the Catalogue of Somatic Mutations in Cancer (COSMIC). It is designed to store and display somatic mutation information and related details and contains information relating to human cancers.Biological StructuresThe identity of available biological structures on drug targets was retrieved from the RCSB Protein Databank for you to easily review what available structures of drug targets exist.Targeted PathwaysDescribed target(s) is/are matched for the involvement in cellular pathways according to BioCarta, KEGG, NCI-Nature and NetPath.MechanismDrug mechanism of actionDevelopmental ProjectsSummary field of developmental projects for the drug, including indication, developmental stage and status.Example:Cancer, myeloma - Phase II Clinical Trial - ActiveCancer, prostate - Phase III Clinical Trial - CeasedDrug DescriptionShort introduction to drugCompound DataCompound type, Chemical name, CAS Number and molecular weightPatent DataAvailable patent information related to the drug is presented here.Fillings and ApprovalsApprovals and submissionsAnalyst commentsDeals & LicensingCollaborations and dealsAvailability for licensingPhase IV DataAvailable Phase IV development data, developmental history and scientific data.Phase III DataAvailable Phase III development data, developmental history and scientific data.Phase II DataAvailable Phase II development data, developmental history and scientific data.Phase I DataAvailable Phase I development data, developmental history and scientific data.Phase 0 DataAvailable Phase 0 development data, developmental history and scientific data.Preclinical DataAvailable preclinical development data, developmental history and scientific data.Discovery DataAvailable discovery development data, developmental history and scientific data.System Requirements- Operating system: Windows (2000/XP/Vista/7/8) and Mac Users are offered Online Access Only- Browser Application (Internet Explorer)- Internet access (to access related internet resources)To order this report: Breast Cancer Drug Pathway Analyzer 2013 .reportlinker.com/p01816738/Breast-Cancer-Drug-Pathway-Analyzer-2013.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_and_Medication__________________________Contact Clare: clare@reportlinker.com US: (339)-368-6001Intl: +1 339-368-6001ReportlinkerWeb site: .reportlinker.com/迷利倉